منابع مشابه
Ppra: an Important Protein of Radiation Resistance in Deinococcus Stimulates Catalase Activity in Escherichia Coli
Deinococcus radiodurans is characterized by its exceptional capacity to tolerate the effects of various DNA damaging agents due to presence of the extraordinary DNA repair mechanism. DNA double strand break repair in Deinococcus radiodurans follows biphasic kinetics. The phase I, a RecA independent phase appears to be a DNA protective and preparatory phase for RecA dependent phase II repair. Pp...
متن کاملActivity, peroxide compound formation, and heme d synthesis in Escherichia coli HPII catalase.
Wild-type Escherichia coli HPII catalase (heme d containing) has 15% the activity of beef liver enzyme per heme. The rate constant for compound I formation with H2O2 is 1.3 x 10(6) M(-1) s(-1). HPII compound I reacts with H2O2 to form O2 with a rate constant of 1.8 x 10(6) M(-1) s(-1). Forty percent of HPII hemes are in the compound I state during turnover. Compound I is reduced by ethanol and ...
متن کاملAntibiotic Tolerance in Escherichia coli Under Stringent Response Correlates to Increased Catalase Activity
Bactericidal antibiotics are known to induce bacterial cell death through the production of reactive oxygen species, which can be neutralized by bacterial oxidative stress control proteins such as catalases. In Escherichia coli, the katE gene encoding catalase is induced by the stringent response pathway. Stringent response is often activated under nutrient and amino acid starvation such as iso...
متن کاملCatalase HPII from Escherichia coli exhibits enhanced resistance to denaturation.
Catalase HPII from Escherichia coli is a homotetramer of 753 residue subunits. The multimer displays a number of unusual structural features, including interwoven subunits and a covalent bond between Tyr415 and His392, that would contribute to its rigidity and stability. As the temperature of a solution of HPII in 50 mM potassium phosphate buffer (pH 7) is raised from 50 to 92 degrees C, the en...
متن کاملNucleotide sequence of Escherichia coli katE, which encodes catalase HPII.
A 3,466-bp nucleotide sequence containing the katE gene of Escherichia coli has been determined. An open reading frame of 2,259 bp was found and was preceded by a potential ribosome-binding site. The predicted N-terminal sequence agreed with the sequence determined by direct amino acid sequencing, and the predicted direction of transcription was confirmed by expression of the gene cloned in bot...
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ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 1952
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.64.4.527-530.1952